Gastric Histomorphological Changes in Albino Rats Administered with Herbal Boobs Enlargement and Lifting Tea

Abstract

The study investigated the histomorphological changes in the stomach of albino rats administered with herbal boobs enlargement and lifting tea, to assess the impact of the herbal tea on behaviour, body weight, and stomach weight. This case-control experimental study was conducted at the Faculty of Medical Laboratory Science, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria. The research period lasted 30 days, with 7, 21, and 30-day periods across the groups. A total of 16 rats were used, divided into four groups (A, B, C, D), with each group containing four rats. Group "A" was not administered with boobs enlargement and lifting tea (control group); group "B" was administered with 0.5ml/kg body weight of boobs enlargement and lifting tea daily for 7 days; group "C" was administered with 0.5ml/kg body weight of boobs enlargement and lifting tea for 21 days; group "D" was administered with 0.5ml/kg body weight of boobs enlargement and lifting tea for 30 days. Stomach tissue was excised for histopathology. Data for body weight and organ weight were analysed using the Statistical Package for the Social Sciences (SPSS). Behavioural observations include drowsiness, increased sleep duration, and reduced locomotion. The body weight results showed statistically significant differences in the initial and final weights of the control group A (p=0.019) and the experimental groups B (p= <0.001), C (p=0.001), and D (p=0.004). The stomach weights showed no statistically significant difference in the experimental groups when compared to the control group, with the p-values of groups B, C, and D being 0.128, 0.116 and 0.211, respectively. Histological analysis of the stomach tissues from the test groups exhibited consistent normal histology with the control group. This study concluded that the experimental rats showed drowsiness, increased period of sleep, and reduced locomotor movement. Experimental and control groups showed an increase in body weight. The mean relative stomach weights revealed no statistically significant difference in the experimental groups when compared to the control groups. Only group B showed a statistically significant difference in the mean relative liver weight. The stomach tissues revealed normal tissue histology across the control and experimental groups. Boobs enlargement tea has no negative effect on the liver and stomach of Albino rats at this concentration and duration.